Fig. 2

Sequence similarity networks for cultivated hosts sequences and their associated environmental sequences. Each node corresponds to a sequence. Two nodes are connected when they share > = 30 % identity, for a hit covering > = 80 % of both of their lengths, with a BLAST score < 1e-5. Sequences are yellow for Archaea, green for Bacteria, orange for environmental homologs whose identity to their closest published relative is lower than 60 %, and grey for environmental homologs whose identity to their closest published relative is higher than 60 %. Left: DUF167 protein, right: cobalamine phosphate synthase