Table 1 Contingency table to validate the assumption that DDLs significantly share disease-related genes or drugs
From: The human disease network in terms of dysfunctional regulatory mechanisms
| Disease pairs correlated to known disease genes or drugs | |||||
|---|---|---|---|---|---|
| DDLs | Non-DDLs | Total | P-value of Fisher’s Exact test | ||
| Disease pairs sharing disease genes | Significant | 910 (81 %) | 2911 (78 %) | 3821 | 0.009085a |
| Non-significant | 209 (19 %) | 821 (22 %) | 1030 | ||
| Total | 1119 | 3732 | |||
| Disease pairs sharing disease drugs | Significant | 348 (47 %) | 1095 (42 %) | 1443 | 0.02307a |
| Non-significant | 397 (53 %) | 1481 (58 %) | 1881 | ||
| Total | 745 | 2576 | |||