Skip to main content

Table 1 Contingency table to validate the assumption that DDLs significantly share disease-related genes or drugs

From: The human disease network in terms of dysfunctional regulatory mechanisms

   Disease pairs correlated to known disease genes or drugs  
   DDLs Non-DDLs Total P-value of Fisher’s Exact test
Disease pairs sharing disease genes Significant 910 (81 %) 2911 (78 %) 3821 0.009085a
Non-significant 209 (19 %) 821 (22 %) 1030  
  Total 1119 3732   
Disease pairs sharing disease drugs Significant 348 (47 %) 1095 (42 %) 1443 0.02307a
Non-significant 397 (53 %) 1481 (58 %) 1881  
  Total 745 2576   
  1. adenotes statistic significance by one-sided Fisher’s Exact test (p < 0.05)