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Fig. 8 | Biology Direct

Fig. 8

From: De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods

Fig. 8

DUF1636 – a Thioredoxin-like fold: a Structural alignment of crystal structure of wild-type thioredoxin-like [2Fe-2S] ferredoxin from Aquifex aeolicus (PDB ID: 1M2A, shown in wheat colour) and modelled DUF1636 (green colour). The conserved cysteine residues in the active site and in the loop region are shown in ball-and-stick. b Multiple sequence alignment of representative sequences of DUF1636 and 1M2A with active site residues marked with blue stars. A red arrow highlights the conserved cysteine residue in the loop region. For clarity, only first 70 residues containing the active site are shown

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