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Fig. 5 | Biology Direct

Fig. 5

From: De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods

Fig. 5

DUF1572 – a putative metalloenzyme: a Structural alignment of YfiT from Bacillus subtilis (PDB ID: 1RXQ, shown in wheat color) and modeled DUF1572 (light blue) highlighting the active site region. Conserved histidine residues coordinating with the Zn metal ion in both structures are shown in ball-and-stick. b Multiple sequence alignment of representative sequences of DUF1572 with the sequence of 1RXQ, highlighting the conserved histidine residues by red stars. A blue circle denotes the additionally conserved active site Aspartate residue

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