Table 2 Selection on mitochondrial functions
From: Mitochondrial activity in gametes and transmission of viable mtDNA
Stage | Level | Mechanism |
|---|---|---|
Gametogenesis | organelle | autophagy of unfit mitochondria selection of high Δψm mitochondria (Bb) replication advantage of wild-type mtDNA |
Gametogenesis Fertilizing gametes | cell | apoptosis of unfit cells fertilization failure |
Zygote Early embryo | organism | development failure |