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Table 2 Selection on mitochondrial functions

From: Mitochondrial activity in gametes and transmission of viable mtDNA

Stage Level Mechanism
Gametogenesis organelle autophagy of unfit mitochondria selection of high Δψm mitochondria (Bb) replication advantage of wild-type mtDNA
Gametogenesis Fertilizing gametes cell apoptosis of unfit cells fertilization failure
Zygote Early embryo organism development failure
  1. Note: the targets of selection are mtDNA and/or nuclear genes for mitochondrial function.