Functional prediction of the
-coumaryl alcohol biosynthesis pathway genes. Both programs used for functional prediction (Argot 2 and ESG) need to predict the correct function for it to be annotated as such. An "F" indicates that an enzyme from that taxonomic group has been biochemically characterized. No single fungi or bacteria harbour homologs for all three enzymes, but all the enzymes are found individually in some representatives of these taxonomic groups. An empty space indicates that no homolog is found in a particular species. Confidence values are derived from the ESG software. * for 4CL, as even enzymes with biochemically demonstrated function are not annotated as such with significant confidence by the softwares used, the figure indicates prediction of ligase activity.