Table 1 The summary of translational parameters calculated in the model and used in this research
Parameter | Description |
|---|---|
L | ORF length in codons |
x | average number of transcripts per cell |
g | ribosome density in number of ribosomes per 100 codons |
w | number of ribosomes attached to a single transcript |
m | transcript mean lifetime |
I | mean translation initiation time |
E | mean translation elongation time |
e | mean time required for elongation of one codon of a transcript |
b | number of proteins produced from a single transcript during its lifespan |
B | total number of protein molecules produced from all transcripts of a gene |
A | number of protein molecules per cell taken from high-throughput studies |
R | average number of proteins produced from a gene per second |