Figure 8

Scheme illustrating subtype upregulated genes predicted from the mRNA-seq data for each cell type. Transcription factor genes are listed in grey in the ‘nucleus’ of each cell, those for receptors are in brown next to the ‘lollipop’ shapes that represent them, and cytokines are the coloured spheres outside each cell. Not all genes known to have roles in the function of a particular cell type are identified as SU genes. Due to their expression at high levels in more than one cell type. For example, this is the case for Rorc which is the master regulator for Th17 differentiation but is also expressed in iTreg cells.