Table 3 Conserved residues between human and yeast orthologs at and around the active site
UniProtKB | Yeast AC | Human active site | Yeast active site | Conservation block |
|---|---|---|---|---|
P13716 | P05373 | 221 R | 232 R | GDR + CYQLPP |
P22830 | P16622 | 383 D | 361 D | +ADLV |
P48637 | Q08220 | 125 R | 128 R | RSDY+ |
P49247 | Q12189 | 160 D | 107 D | DGADEVD |
Q96GX9 | P47095 | 47 G | 39 G | TGTGGGIS + K |
Q9Y2Z4 | P48527 | 243 G | 261 G | +Q + GG + DQ |