Table 9 Human proteins in Tuberculosis pathway that are targeted by the predicted host-pathogen PPIs
From: Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions
H. Sapiens protein | M. Tuberculosis protein | Consensus score | Cellular compartment | Molecular function |
|---|---|---|---|---|
CTSD | Rv2987c | 3 | GO:0005737 cytoplasm | GO:0016787 hydrolase activity |
NFKB1 | Rv0155 | 3 | GO:0005737 cytoplasm | GO:0005515 protein binding |
CR1 | Rv1589 | 3 | GO:0044459 plasma membrane part | GO:0005515 protein binding |
ITGB2 | Rv1133c | 3 | GO:0005737 cytoplasm | GO:0005515 protein binding |
CD74 | Rv0685 | 1 | GO:0005737 cytoplasm | GO:0005515 protein binding |
RAB5A | Rv1020 | 2 | GO:0005737 cytoplasm | GO:0005515 protein binding |
RAB5C | Rv1122 | 3 | GO:0005737 cytoplasm | GO:0005515 protein binding |
JAK1 | Rv1340 | 3 | GO:0005737 cytoplasm | GO:0005515 protein binding |
TGFB1 | Rv1384 | 3 | GO:0005737 cytoplasm | GO:0005515 protein binding |
CORO1A | Rv0685 | 1 | GO:0005737 cytoplasm | GO:0005515 protein binding |