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Figure 2 | Biology Direct

Figure 2

From: Impairment of translation in neurons as a putative causative factor for autism

Figure 2

Schematic representation of the interplay between the rare codons in human genes associated with ASD and increased exposure to an unidentified neurotoxin(s). These rare variations in genes involved in neuron development are hypothesized to contribute to the pathogenesis of ASD in the presence of aggressive chemical background whereas in the absence of such background these rare variations are unlikely to cause noticeable phenotypic effects.

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