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Table 2 Potential candidates for local orphan enzymes retrieved by PRIAM

From: Profiling the orphan enzymes

 

       Archaea

       Bacteria

       Eukaryota

 

local orphan EC

not observed EC

local orphan EC

not observed EC

local orphan EC

not observed EC

Total number

79

3774

133

1521

299

1348

Number of predictable

56

2247

115

817

150

718

Number of predicted

17

475

35

203

88

333

Percent of predicted

30%

21%

30%

25%

59%

46%

Number of candidate

400

9406

2929

11451

2996

9727

  1. Not observed EC numbers correspond to entries than have never been associated to a protein or an organism in the superkingdom. Predictable EC numbers are entries having an associated PRIAM profile. A predicted EC number is an entry for which PRIAM detected a significant hit with at least one protein sequence (see Additional file 1: Figure S1.3).