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Table 4 Frequency of best motifs discovered using MERCI software in IFN-γ epitopes and Rest of cytokine inducing epitopes from IFNgOnly dataset

From: Designing of interferon-gamma inducing MHC class-II binders

Class of Motifs

Found in IFN Epitopes

Frequency

Found in Rest-epitopes

Frequency

None

F-QP-Q

42

ANKIR

17

Koolman-Rohm

R[basic]-R-[aliphatic] [neutral]

51

[neutral]K[aliphatic]RE

17

Betts-Russell (Hydorphobic)

YR[aliphatic]

63

[hydrophobic]-N[hydrophobic][small]K-[R]

29

Betts-Russell (Polar)

[polar]-YR[aliphatic]

53

[polar]-N[hydrophobic] [small]K-R

28

Betts-Russell (Small)

small-YR[aliphatic]

54

PN[hydrophobic][small]-[positive]-[polar]

32

  1. Negative sign (−) = represents the gaps at that position.