Table 2 Frequency of best motifs discovered using MERCI software in IFN-γ epitopes and non-epitopes
From: Designing of interferon-gamma inducing MHC class-II binders
Class of Motifs | Found in IFN epitopes | Frequency | Found in non-epitopes | Frequency |
|---|---|---|---|---|
None | QPQ-Q-P-Q | 41 | IS-L-M | 40 |
Koolman-Rohm | Q-[aliphatic]-[neutral]-P[neutral]-Q | 53 | [aliphatic]-I-[aliphatic]L[aliphatic][aliphatic][aliphatic]-[aliphatic] | 66 |
Betts-Russell (Hydorphobic) | [aliphatic][polar][small][polar][aliphatic][polar][small]E | 37 | [hydrophobic]I[hydrophobic][aliphatic][aliphatic][hydrophobic][hydrophobic][hydrophobic] | 89 |
Betts-Russell (Polar) | [polar][hydrophobic][hydrophobic][polar][small][small][aliphatic][small][small]E | 32 | [polar][aliphatic][hydrophobic][hydrophobic][hydrophobic][aliphatic][hydrophobic][hydrophobic][charged][hydrophobic] | 40 |
Betts-Russell (Small) | [small][hydrophobic][polar][polar][charged]W[polar] | 31 | [small][aliphatic]I[aliphatic][hydrophobic][hydrophobic][small][hydrophobic] | 51 |