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Table 2 Frequency of best motifs discovered using MERCI software in IFN-γ epitopes and non-epitopes

From: Designing of interferon-gamma inducing MHC class-II binders

Class of Motifs Found in IFN epitopes Frequency Found in non-epitopes Frequency
None QPQ-Q-P-Q 41 IS-L-M 40
Koolman-Rohm Q-[aliphatic]-[neutral]-P[neutral]-Q 53 [aliphatic]-I-[aliphatic]L[aliphatic][aliphatic][aliphatic]-[aliphatic] 66
Betts-Russell (Hydorphobic) [aliphatic][polar][small][polar][aliphatic][polar][small]E 37 [hydrophobic]I[hydrophobic][aliphatic][aliphatic][hydrophobic][hydrophobic][hydrophobic] 89
Betts-Russell (Polar) [polar][hydrophobic][hydrophobic][polar][small][small][aliphatic][small][small]E 32 [polar][aliphatic][hydrophobic][hydrophobic][hydrophobic][aliphatic][hydrophobic][hydrophobic][charged][hydrophobic] 40
Betts-Russell (Small) [small][hydrophobic][polar][polar][charged]W[polar] 31 [small][aliphatic]I[aliphatic][hydrophobic][hydrophobic][small][hydrophobic] 51
  1. Negative sign (−) = represents the gaps at that position.