Deep transcriptome-sequencing and proteome analysis of the hydrothermal vent annelid Alvinella pompejana identifies the CvP-bias as a robust measure of eukaryotic thermostability

Table 5 Correlation of CvP-bias with the body temperature of homeothermic vertebrates

Species	Number of sequences	CvP-bias	Tm-Index	IUPred	IVYWREL	Body temperature °C
HUMAN	50 006	0.93	0.9	0.31	36.87	37°C
MOUSE	36 368	0.97	0.93	0.29	37.16	37°C
TURTR (bottle-nosed dolphin)	307	0.99	0.79	0.28	38.8	36.8°C
RAT	30 926	1.02	0.97	0.28	37.17	37°C
BOVIN	23 358	1.34	0.96	0.27	37.6	37°C
CHICK	19 671	1.42	0.94	0.28	37.3	41°C
CANFA (dog)	24 002	1.43	0.96	0.28	37.5	37°C
PIG	24 692	1.61	0.98	0.28	37.43	37°C
MELGA (turkey)	15 899	1.72	0.94	0.27	37.66	41°C
TAEGU (zebra finch)	16 717	2.32	0.97	0.27	37.72	41°C
	Pearson’s r	0.71	0.23	−0.44	0.02

Validation of CvP-bias with body temperatures of homeothermic vertebrates. The number of sequences as well as the mean values of the indicated measures are shown for 10 vertebrate species. Pearson’s correlation coefficients of thermostability measures to body temperature are shown.

ISSN: 1745-6150