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Table 4 Correlation of CvP-bias differences with experimentally determined Tm value differences for various orthologous protein pairs

From: Deep transcriptome-sequencing and proteome analysis of the hydrothermal vent annelid Alvinella pompejana identifies the CvP-bias as a robust measure of eukaryotic thermostability

Protein   Thermophilic (A. pompejana or C. thermophilum) Mesophilic (human,S. cerevisiae or T. reesei) Difference
Rrp4 (A. pompejana vs. human) CvP-bias 0.408 6.122 5.714
  Tm 38°C 43.1°C 5.1
Pol η (A. pompejana vs. human) CvP-bias 5.71 3.67 −2.04
  Tm 49°C 43°C −6
Collagen (A. pompejana vs. human) CvP-bias 8.696 5.804 −2.892
  Tm 45-46°C 38-42°C −3 to −8
U2AF65 (A. pompejana vs. human) CvP-bias 11.90 5.68 −6.22
  Tm 47°C 43°C −4
Nup170 (C. thermophilum vs. S. cerevisiae) CvP-bias −1.13 −4.86 −3.73
  Tm 57°C 36°C −21
Nup192 (C. thermophilum vs. S. cerevisiae) CvP-bias 3.47 −3.33 −6.8
  Tm 57°C 36°C −21
Xylanase (C. thermophilum vs. Trichoderma reesei) CvP-bias −20.276 −22.523 −2.24
  Tm 60°C 50°C −10
  1. Validation of CvP-bias with experimentally determined thermal stabilities for orthologous protein pairs from refs. [8, 30].