Figure 13

CTLs Spatial density in presence of immunoevasive mechanisms. Plots showing the distribution of CTLs within the tissue at times corresponding to 100, 400, 700, and 1100 days respectively. These plots illustrate the spatiotemporal onset of immunoevasion. The final plot at t=1100 should be compared to the equivalent plot in Figure 10, whereas the plot in the left panel, referring to time t=700 days, is analogous to the equivalent plot in Figure 10. These plots suggests that the onset of immunoevasion occurs after t=700 days. Parameter values p _N =0.75 and $k_i^{+}=\text{constant}$. Solid line with chemorepellent, dashed line without.