Figure 2From: IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lprmiceWestern blot for γ3 heavy chain (IgG3) in serum from mice bearing zero (-/-), one (+/-), or two (+/+) wild-type (functional) γ3 heavy chain alleles by PCR genotyping assay. Lane 1, markers; 2-6, γ3 +/+; 7-8, γ3 +/-; 9-10, γ3 -/-.Back to article page