Skip to main content

Table 2 Invariant genes (between datasets) among common leading edge and Fisher-selected genes: Wang and van de Vijver data sets - see Informative Genes section for summary citations below

From: Pathway-based classification of cancer subtypes

Gene symbol

Full name

Summary

MAD2L1

Mitotic arrest-deficient2, S. Cerevisiae, homolog-like 1

Overexpressed in breast and ovarian cancers [31, 32]

PTTG1

Pituitary tumor-transforming gene 1

Oncogene related with breast cancer [33]

BUB1B

Budding uninhibited by benzimidazoles1, S. Cerevisiae homolog of beta

Overexpressed in breast cancer [31]

SQLE

Squalene epoxidase

Overexpressed in breast cancer and significantly inversely related to distant metastasis-free survival in early stage breast cancer [34]

E2F1

E2F transcription factor 1

Related with breast cancer outcome [35]

TSTA3

Tissue specific transplantation antigen P35B

Conserved in several breast cancer subtypes [36]

  1. For each dataset common Fisher and leading edge genes were selected, and then intersected between the two datasets. Genes previously connected to cancer (with summaries) are listed here, and remaining genes are included in (Additional file 1: Table S1).