Dependence of model outcome on the initial virus load. (a) Two time series that only differ in the initial virus load. In case of the higher initial virus load, the virus population persists. In case of the lower initial virus load, the virus population goes extinct. (b) Graphic showing how the dependence on initial virus load is changed by the degree to which additional resident viruses increase the burst size of infected cells, g. In the stripy area, the virus goes extinct. In the white area initial virus load is sufficiently high and a successful infection is established. Panels i-iii show cases with increasing viral infection rates. Parameters were chosen as follows. (a) λ = 10; d = 0.1; β = 0.02; a = 0.2; k = 4; u = 1; ϵ = 1; g = 0.75; η = 0.5; n = 200. x(0) = λ/d; y
(0) = 0, v(0) = 25 vs 10. (b) λ = 10; d = 0.1; a = 0.2; k = 4; u = 1; ϵ = 1; g = 0.75; η = 0.5; n = 200. (i) β = 0.015, (ii) β = 0.02, (iii) β = 0.023.