Figure 7
Average number of false positives as a function of nominal E-value. The plot shows the relationship between the nominal E-values reported by the search methods and actual E-values, estimated from search results. For a particular search method and nominal E-value x, the actual E-value is estimated by the mean number of false positive alignments returned with reported E-value ≤ x. The vertical dashed lines show nominal E-value thresholds at which the various search methods return 0.3 false positives per query (shown by the horizontal dashed line).