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Table 1 Mendelian genetics from the perspective of evolutionary biology.

From: The existence of species rests on a metastable equilibrium between inbreeding and outbreeding. An essay on the close relationship between speciation, inbreeding and recessive mutations

Type of mutation

Usual phenotype

Estimated Frequency

(in mammalian genomes)

Silent

None

97 - 99.9%

Gene inactivation

Recessive

3 - 0.1%

New gene function

Dominant

10-4 - 10-5

Gene dosage effect

Co-recessive

3 - 0.1%

Change of function

Co-dominant

10-4 - 10-5