Gene gain and loss events in Rickettsia and Orientiaspecies

Biology Direct

Table 1 Genes gained by Rickettsiales.

riCOGs	donor species	annotation	biological process	gained by	lost by
riCOG01601	γ -proteobacteria	unknown	unknown	R. canadensis
riCOG01580	δ-proteobacteria	unknown	unknown	R. akari, R. felis
riCOG00373	Bacteroidetes	unknown	unknown	R. canadensis, SFG, Orientia Ikeda	R. massiliae
riCOG00835	Cyanobacteria, Acidobacteria	toxin of toxin antitoxin	toxin of toxin antitoxin	SFG
riCOG00983	γ-proteobacteria	metK	S-adenosylmethionine synthesis	R. akari, R. felis, TG	R. prowazekii
riCOG01685	Eukaryotes	leucine-rich repeats	unknown	R. felis, R. bellii
rioriCOGs
rioriCOG00831	Canarypox virus	ankyrin-repeat containing protein	protein-protein interaction motif	Orientia spp.
rioriCOG00862	protists	ankyrin-repeat containing protein	protein-protein interaction motif	Orientia spp.
rioriCOG00673	Cyanobacteria	transposase & inactivated derivative	transposase activity	Orientia spp., R. endosymbiont of Ixodes scapularis

Six riCOGs probably transferred by different bacteria, animals and plants to rickettsial species and 3 rioriCOGs probably transferred by gamma-proteobacteria species, viruses and protists to the Orientia genus. Transferred genes have various functions including protein-protein interaction and metabolic activity. HGT took place at different levels of evolution and at some cases it was followed by gene loss in some species.

ISSN: 1745-6150