Figure 5

Relationship between function and sign of values of ortholog products obtained with polarity. From left to right, proportions of functional classes grouped into Metabolism (1, amino acid biosynthesis; 2, nucleotide biosynthesis; 3, fatty acid biosynthesis; 4, cofactor biosynthesis; 5, central intermediary metabolism; and 6, energy generation), Information (7, DNA metabolism; 8, transcription; 9, translation; and 10, transcriptional regulators), Processes (11, transport; 12, cellular envelope synthesis; and 13, other cellular processes), and Hypothetical functions (14). Bar colors: green, negative; red, positive. Asterisks denote significant differences with p < 0.05, Fisher's exact test.