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Figure 4 | Biology Direct

Figure 4

From: A mathematical model for targeting chemicals to tissues by exploiting complex degradation

Figure 4

Plot showing A 0 (0) (see equation (9a)) for a range of values of λ 2 and λ 3 (with μ A / δ A = 1). Note that the largest values of A0(0) are achieved when λ3 = 0 (no removal/consumption of a) and λ2 is large (rapid breakdown of c), in which case A S (0) → 1 + μ A /δ A = 2. Hence the highest levels of a at the centre of the tissue occur when the rate of complex breakdown (λ2) is rapid, and the rate of consumption of a (λ3) is minimised.

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