Relationship of IIP
with IC50 and k
. log IIPmin plotted against (A) log IC50 (represented by filled circles) or (B) log kdrug (represented by stars; with kdrug calculated as (δpre+kHIV)/(IC50)m) for 25 different antiretroviral drugs (listed in Supplemental Table 1 of Additional File 1 and color-coded by drug class). Line of best fit through the data points in black. IIP and IC50 data from reference .