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Table 1 Function of milk proteins

From: Shift in the isoelectric-point of milk proteins as a consequence of adaptive divergence between the milks of mammalian species

Protein

Role

Milk fraction

α-S1-casein, β-caseinm and κ-casein

~80% of bovine and 20-45% of human milk protein. Phosphoprotein carriers of minerals and trace elements.

Casein micelles

α-lactalbumin

Calcium and other carrier, lactose synthesis [26]

Whey

Lactoferrin

Iron and other metal binding [27], antimicrobial, antiviral [28], antioxidative, cell growth regulator

Whey

Lactadherin

Also known as Milk Fat globule factor 8 (Mfge8); bactericidal and apoptotic properties [29].

Milk fat globule; digestion resistant

Mucin 1

Modulates bacterial adhesion [29]

Milk fat globule; digestion resistant

Xanthine oxidase/dehydrogenase

Fat globule secretion [30] Innate immunity/oxidation [31]

Milk fat globule

Butyrophilin

~40% of protein in Milk Fat Globule Membrane; fat globule secretion [29]

Milk fat globule; rapidly degraded