Figure 5From: Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systemsStructural organization of Cas9 protein families and their homologs. Homologous regions are shown by the same color. Distinct sequence motifs are denoted by the corresponding conserved amino acid residues above the respective domains (when the same conserved amino acid occurs in different motifs, one is marked by an asterisk to avoid confusion).Back to article page