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Table 1 Annotation terms identified to be pertinent to XLMR using a literature- and data-mining approach

From: A computational approach to candidate gene prioritization for X-linked mental retardation using annotation-based binary filtering and motif-based linear discriminatory analysis

ANNOTATION TERM CATEGORIES1

Anatomical site

Biological Process

Phenotype

Animal model homology

Developmental

Development

Seizures

Phenotype

Liver

Transcription

Epilepsy

Behaviour/Neurological

Central nervous system

Metabolism

Acidosis

Nervous system related

Respiratory

Phosphorylation

Microcephaly

Embryogenesis

Cerebellum

Brain development

Tremor

 

Kidney

  

Timing

Hippocampus

  

Pre-Embryonic

Spinal cord

  

Embryonic

Cerebral cortex

  

Fetal

Testis

   

Brain stem

  

Anatomy

Peripheral nerve

  

2TS8-9 Ectoderm

Cerebrum

  

TS10-13 Neural Ectoderm

Substantia nigra

  

TS14-26 CNS

Cardiovascular

   

Adrenal gland

   

Thyroid

   

Ovary

   

Amygdala

   

Musculoskeletal

   

Ganglion

   

Hypothalamus

   
  1. 1These terms were used to extract gene lists that were compared to all X chromosome genes in a binary filtering process. Annotation terms are divided into four categories based on their ontological classification.
  2. 2TS - Theiller stage: A term used to denote the stage of development of a mouse as described by Theiler in "The House Mouse: Atlas of Mouse Development" (Springer-Verlag, New York, 1989)
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Biology Direct

ISSN: 1745-6150

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