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Table 4 Gene loci identified to be both under positive selection and homologous recombination.

From: Interplay of recombination and selection in the genomes of Chlamydia trachomatis

Locus Tag

Locus

Gene Annotation

Positive Selection Analysis

FDR-p-value (Test 2 FDR p-value)

Recombination Method

Smallest significant p-value

CT681

ompA

major outer membrane protein

Test 1

0.002606405

NSS, MaxChi GeneCon, PHI

0.00E+00

CT824

-

insulinase family zinc metalloprotease

Test 1

9.81E-05

NSS, PHI

5.00E-03

CT852

yhgN

Yhgn Family Protein/putative integral membrane protein

Test 2

(Clade 1)

0.01888237

MaxChi, GeneCon

0.00E+00

CT869

pmpE

polymorphic outer membrane protein

Test 1

1.55E-32

NSS, MaxChi GeneCon, PHI

0.00E+00

CT870

pmpF

polymorphic outer membrane protein

Test 1

1.55E-32

NSS, MaxChi GeneCon, PHI

0.00E+00

CT875

-

hypothetical protein

Test 1,

Test 2

(Clade 4)

2.93E-07 (0.001)

MaxChi

8.00E-03

CT011

-

hypothetical protein

Test 1,

Test 2

(Clade 2)

0.008772363

MaxChi, GeneCon

0.00E+00

CT033

recD_1

exodeoxyribonuclease V alpha chain

Test 2

(Clade 4)

0.0316283

NSS

4.40E-02

CT049

-

hypothetical protein

Test 1

6.42E-06

NSS, MaxChi GeneCon, PHI

0.00E+00

CT107

mutY

A/G-specific adenine DNA glycosylase

Test 1

2.44E-10

MaxChi, GeneCon

3.00E-04

CT112

pepF

oligoendopeptidase F

Test 2

(Clade 4)

0.014

GeneCon

0.0127

CT115

incD

inclusion membrane protein D

Test 1,

Test 2

(Clade 1)

4.51E-04 (3.56E-04)

MaxChi

1.10E-02

CT144

-

hypothetical protein

Test 1

5.78E-13

NSS, MaxChi GeneCon, PHI

0.00E+00

CT244

-

hypothetical protein

Test 1,

Test 2

(Clade 3)

2.95E-06 (1.56E-08)

MaxChi, GeneCon

0.00E+00

CT288

-

Hypothetical protein/candidate inclusion membrane protein

Test 1,

Test 2

(Clade 4)

2.95E-06 (0.0058)

NSS

5.00E-03

CT315

rpoB

DNA-directed RNA polymerase subunit beta

Test 2

(Clade 4)

0.0067

MaxChi

2.10E-02

CT448

secD/secF

bifunctional preprotein translocase subunit SecD/SecF

Test 2

(Clade 3)

2.50E-05

MaxChi, GeneCon

0.00E+00

CT456

-

hypothetical protein/translocated actin-recruiting protein (tarp)

Test 1,

Test 2

(Clade 1)

0.0021 (6.30E-06)

NSS, MaxChi, GeneCon

0.00E+00

CT470

recO

DNA repair protein RecO

Test 1

0.0036

MaxChi

4.00E-03

CT551

dacC

D-alanyl-D-alanine carboxypeptidase

Test 2

(Clade 4)

0.051

MaxChi

2.00E-02

CT580

-

hypothetical protein/putative integral membrane protein

Test 1

1.46E-09

MaxChi

1.10E-02

CT604

groEL_2

60 kDa chaperonin GroEL2

Test 1,

Test 2

(Clade 3)

0.006 (1.35E-15)

MaxChi, GeneCon

0.00E+00

CT619

-

hypothetical protein

Test 2

(Clade 1)

0.008

NSS, MaxChi, GeneCon

0.00E+00

  1. GeneCon -> GENECONV; NSS -> Neighbor Similarity Score; MaxChi -> Maximum χ2; PHI -> Pairwise Homoplasy Test