Skip to main content

Table 1 Comparisons between the intron-containing genes and the intronless genes of Saccharomyces cerevisiae.

From: Why eukaryotic cells use introns to enhance gene expression: Splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity

  Intron-containing genes Intronless genes P(Mann-Whitney U test)
mRNA abundance (molecules/cell) 4.9 1.3 10-33
  23 ± 38 4.2 ± 18  
Nascent transcription rate (molecules/min) 0.27 0.12 7 × 10-28
  0.37 ± 0.33 0.16 ± 0.20  
RNA polymerase II density (molecules/kb) 0.18 0.077 7 × 10-28
  0.25 ± 0.22 0.11 ± 0.13  
  1. Data from [37]. In each item, we show the median value and the average ± standard deviation.