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Table 1 MicroRNAs differentially expressed (P < 0.05) between MM (n = 33) and controls (n = 9) depicting chromosomal location and where relevant their expression within a microRNA cluster.

From: MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

Order microRNA adj. P value Fold change Chromosome Cluster
1 miR-1 5.41E-06 3.15 20q13.33/18q11.2 1-1, 133a
2 miR-203 2.09E-05 2.64 14q32.33 -
3 miR-342 2.25E-05 3.94 14q32.2 -
4 miR-631 2.25E-05 4.24 15q24.2 -
5 miR-200a 3.17E-05 5.50 12p13.31 141-200c
6 miR-34c 5.95E-05 3.31 11q33.1 34b-34c
7 miR-361 5.95E-05 12.66 Xq21.2 -
8 miR-9* 7.64E-05 4.48 1q22/5q14.3/15q26.1 -
9 miR-200b 8.52E-05 4.97 12p13.31 141-200c
10 miR-9 8.52E-05 5.07 1q22/5q14.3/15q26.1 -
11 miR-151 1.19E-04 2.67 8q24.3 -
12 miR-218 1.42E-04 3.96 4p15.31/5q34 -
13 miR-28-3p 1.90E-04 2.52 3q28 -
14 miR-200c 2.10E-04 5.26 12p13.31 141-200c
15 miR-21 2.72E-04 2.45 17q23.1 -
16 miR-378 2.72E-04 2.96 5q33.1 -
17 miR-548d-5p 2.72E-04 3.10 8q24.13/17q24.2 -
18 miR-621 2.72E-04 9.64 13q14.11 -
19 miR-140-5p 3.91E-04 2.78 16q22.1 -
20 miR-634 4.77E-04 2.25 17q24.2 -
21 miR-616 6.16E-04 2.69 12q13.3 -
22 miR-130a 7.81E-04 2.48 11q12.1 -
23 miR-593 7.81E-04 3.29 7q32.1 -
24 miR-708 7.81E-04 3.32 11q14.1 -
25 miR-200a* 7.81E-04 4.08 12p13.31 141-200c
26 miR-340 9.03E-04 2.41 5q35.3 -
27 miR-760 1.12E-03 2.44 1p22.1 -
28 miR-885-3p 1.39E-03 2.55 3p25.3 -
29 miR-590-3p 1.42E-03 3.50 7q11.23 -
30 miR-885-5p 1.61E-03 3.34 3p25.3 -
31 miR-221 2.36E-03 2.85 Xp11.3 221-222
32 miR-7 2.36E-03 3.66 9q21.32/15q26.1/19p13.3 -
33 miR-188-5p 2.94E-03 2.18 Xp11.23 532-660
34 miR-338 2.94E-03 2.35 17q25.3 338-657
35 miR-222 2.94E-03 2.47 Xp11.3 221-222
36 miR-99a 2.94E-03 3.47 19q13.33 99b-125a
37 miR-891a 3.06E-03 2.31 Xq27.3 890-891
38 miR-452 3.77E-03 2.57 Xq28 452-224
39 miR-98 4.09E-03 3.04 Xp11.22 98-let-7f
40 miR-629 4.09E-03 3.14 15q23 -
41 miR-515-3p 4.11E-03 5.90 Xq27.3 -
42 miR-192 4.20E-03 2.44 11q13.1 192-194
43 miR-454 4.36E-03 2.82 17q22 -
44 miR-151-3p 4.59E-03 2.22 8q24.3 -
45 miR-141 5.20E-03 3.37 12p13.31 141-200c
46 miR-128b 5.35E-03 2.25 2p21.3/3p22.3 -
47 miR-1227 5.64E-03 2.82 19p13.3 -
48 miR-128a 6.51E-03 2.82 2p21.3/3p22.3 -
49 miR-205 6.94E-03 3.15 1q32.2 -
50 miR-27b 7.30E-03 2.81 9q22.32 23b-24
51 miR-608 7.67E-03 2.38 10q24.31 -
52 miR-432 7.99E-03 2.41 14q32.2 337-136
53 miR-220 8.08E-03 2.86 Xq25 -
54 miR-135a 8.30E-03 2.80 3p21.1/12q23 -
55 miR-34a 8.42E-03 2.58 1p36.22 -
56 miR-28 8.72E-03 1.94 3q28 -
57 miR-412 9.41E-03 2.12 14q32.2 323-656
58 miR-877 9.84E-03 1.91 6p21.33 -
59 miR-628-5p 1.04E-02 2.09 15q21.3 -
60 miR-532-3p 1.06E-02 1.95 19q13.41 -
61 miR-625 1.15E-02 2.11 14q23.3 -
62 miR-34b 1.19E-02 2.07 11q33.1 34b-34c
63 miR-31 1.28E-02 2.62 9p21.3 -
64 miR-181a 1.46E-02 2.05 1q32.1/9q33.3 181a-181b
65 miR-32 1.46E-02 2.80 9q31.3 -
66 miR-106b 1.51E-02 2.48 7q22.1 106b-25
67 miR-146a 1.52E-02 2.14 5q33.3 -
68 miR-210 1.52E-02 2.87 11p15.5 -
69 miR-499-5p 1.54E-02 6.60 20q11.2 -
70 miR-140 1.58E-02 2.35 16q22.1 -
71 miR-188 1.68E-02 1.99 Xp11.23 532-660
72 miR-610 1.68E-02 2.54 11p14.1 -
73 miR-27a 1.70E-02 2.45 19p13.12 24-23a
74 miR-142-5p 1.70E-02 2.47 17q22 -
75 miR-603 1.75E-02 1.80 10p12.2 -
76 miR-660 1.75E-02 2.13 Xp11.23 532-502
77 miR-19a 1.75E-02 2.79 13q31.3/Xq26.2 17-92/106a-363
78 miR-649 1.78E-02 1.91 22q11.21 -
79 miR-140-3p 1.98E-02 2.12 16q22.1 -
80 miR-300 2.00E-02 2.30 14q32.31 543-655
81 miR-335 2.11E-02 2.11 7q32.2 -
82 miR-206 2.20E-02 1.84 6p12.2 206-133b
83 miR-20b 2.20E-02 2.18 13q31.3/Xq26.2 17-92/106a-363
84 miR-130b 2.25E-02 2.19 22q11.21 301b-130b
85 miR-183 2.40E-02 2.50 7q32.2 183-182
86 miR-652 2.44E-02 2.36 Xq22.3 -
87 miR-133b 2.44E-02 2.41 6p12.2 133b-206
88 miR-191* 2.56E-02 1.97 3p21.31 425-191
89 miR-19b 2.58E-02 2.62 13q31.3/Xq26.2 17-92/106a-363
90 miR-212 2.71E-02 1.97 17p13.3 212-132
91 miR-194 2.73E-02 2.09 1q41/11q13.1 215-194/192-194
92 miR-100 2.82E-02 2.82 11q24.1 100-let7a
93 miR-1234 2.88E-02 1.91 8q24.3 -
94 miR-182 2.96E-02 2.29 7q32.2 183-182
95 miR-888 3.28E-02 2.15 5q33.1 -
96 miR-30e-5p 3.55E-02 2.27 1p34.2 30e-30c
97 miR-574 3.60E-02 2.16 4p14 -
98 miR-135b 3.60E-02 2.31 1q32.1 -
99 miR-125b 3.60E-02 2.43 11q24.1/21q21 -
100 miR-502 3.77E-02 1.79 Xp11.23 500-502
101 miR-320 3.77E-02 1.74 8p21.3 -
102 miR-421 3.77E-02 1.76 Xq13.2 421-374b
103 miR-129-3p 3.77E-02 1.80 7q32.1/11p11.2 -
104 miR-190b 4.03E-02 2.02 1q21.3 -
105 miR-18a 4.44E-02 2.21 13q31.3/Xq26.2 17-92/106a-363
106 miR-549 4.44E-02 2.25 15q25.1 -
107 miR-338-5p 4.45E-02 1.97 17q25.3 338-657
108 miR-576-3p 4.60E-02 4.80 4q25 -
109 miR-133a 4.62E-02 2.32 6p12.2 133b-206
-1 miR-373* 1.39E-03 -1.82 19q13.42 371-373
-2 miR-378* 2.43E-03 -3.34 5q33.1 -
-3 miR-143 8.83E-03 -1.80 5q33.1 -
-4 miR-15a 1.51E-02 -1.67 13q14 15a-16
-5 miR-337 1.52E-02 -1.65 14q32.2 493-432
-6 miR-223 1.54E-02 -3.82 Xq12 -
-7 miR-369-3p 1.55E-02 -1.83 14q32.31 323-656
-8 miR-520g 1.58E-02 -1.90 19q13.42 517-518
-9 miR-485-5p 1.75E-02 -3.18 19q13.42 517-518
-10 miR-524* 1.86E-02 -1.83 19q13.42 517-518
-11 miR-520h 2.20E-02 -1.98 19q13.42 517-518
-12 miR-516-3p 2.20E-02 -1.81 19q13.42 517-518
-13 miR-519d 2.20E-02 -1.78 19q13.42 517-518
-14 miR-371-3p 2.34E-02 -3.58 19q13.42 517-518
-15 miR-455 2.88E-02 -1.88 9q32 -
-16 miR-520b 2.96E-02 -1.85 19q13.42 517-518
-17 miR-518d 3.28E-02 -2.09 19q13.42 517-518
-18 miR-624 3.28E-02 -1.56 14q12 -
-19 miR-296 3.59E-02 -1.85 21q22.12 -
-20 miR-16 4.69E-02 -1.83 13q14 15a-16
  1. Positive values are up-regulated in MM and negative values down-regulated. MicroRNAs in common with Zhou et al [11] are denoted in red font and Pichiorri et al [12] in bold font.