Figure 1

The Oct4/Pou5f1 Regulatory Region: Regulation and Repeats. The Oct4/Pou5f1 regulatory region, displayed using the UCSC genome browser [27]. The information on the experimentally validated regulatory elements is displayed below the genome coordinates, using grey blocks and green text in a format consisting of an abbreviated reference (see Table 2), the name of the transcription factor (as it appears in the reference) & its standardized name (if they are not identical), and a specific identifier assigned in the reference (e.g. M1 and M3 distinguishing the two Tfc3 binding sites). Also, the conserved regions CR1 to CR4 and the 2A distal element (DE) and the 1B proximal element (PE) are listed [59]. Below these annotations, repeat information and GC content are shown (moreover, no microRNAs, no ORegAnno [28] annotation or Rest binding [80] is available).