Figure 4

A representative set of pS/pT clustered-rich proteins. Short segments (75 amino acids each) that are exceptionally rich in clustered phosphosites are shown. These proteins have >5 proximal phosphosites clusters and >5 independent evidence from the literature. We marked clusters by a stringent definition where the distance between two consecutive pS/pT sites is at most n+3 (n denotes the position of pS/pT). The frames around the phosphosites denote the following: black, only one pair of pS/pT; orange, extended cluster according to the maximal distance of n+3 between neighboring pS/pT sites; blue, a mixed cluster of pS/T and pY. Phosphosites that are inferred from the identification of phosphosites in a close homologue are marked in a black font. For a complete list of clustered-rich proteins see Additional file 1