The ancient function of RB-E2F Pathway: insights from its evolutionary history

Biology Direct

Table 1 Summary of the distribution and sub-grouping of E2F1-6 Family proteins in different organisms

	E2f1-6 family
M brevicollis	E2F-Mb (gi\|167523471)
	E2F1/2/3 subgroup				E2F4/5 subgroup
T. adhaerens	E2F1/2/3-Ta (gi\|196010483)				E2F4/5-Ta (gi\|196012606)
N. vectensis	E2F1/2/3-Nv (gi\|156371340)				E2F4/5-Nv (gi\|156368461)
C. elegans					EFL-1-Ce (gi\|17559226)
D.me lanogaster	E2F1-Dm (gi\|24648770)				E2F2-Dm (gi\|17137542)
S. purpuratus					E2F4/5-Sp (gi\|115696783)
C. intestinalis	E2F1/2/3-Ci (gi\|118343729)				E2F4/5-Ci (gi\|118343737)
B. floridae	E2F1/2/3-Bf (gi\|260790430)				E2F4/5-Bf (gi\|260798626)
	E2F1	E2F2	E2F3	E2F6	E2F4	E2F5
T. nigroviridis	ENSTNIT00000007876	ENSTNIT00000020634	ENSTNIT00000012687	ENSTNIT00000008935 ENSTNIT00000013829	ENSTNIT00000002389 ENSTNIT00000002758	ENSTNIT00000004791
D. rerio			gi\|220673319	gi\|71892405	gi\|47087407	gi\|68533607
X. tropicalis	ENSXETT00000046332		gi\|58331835		gi\|167560905	gi\|188528909
G. gallus	gi\|45382583		gi\|118086362	ENSGALT00000031596	gi\|118096144	gi\|71896455
R. norvegicus	gi\|189217865		gi\|212549627	gi\|109479090	ENSRNOT00000021145
M. musculus	gi\|6681243	gi\|29244208	gi\|83523736	gi\|237681138	gi\|22507329	gi\|31982405
B. taurus	gi\|194672360	gi\|76611569	gi\|76663083	gi\|116003911	gi\|115497534
C. familiaris	gi\|73992245	ENSCAFT00000021059	gi\|74004128	gi\|73980432	gi\|73957515	gi\|73999542
H. sapiens	gi\|12669911	gi\|4758226	gi\|4503433	gi\|109637795	gi\|12669915	gi\|134142811

According to results from Figure 2A, E2F1-6 family proteins (accession numbers from genbank or Ensembl database) identified in M. brevicollis and 16 metazoan organisms were listed. The detail explains could be found in main text

ISSN: 1745-6150

	E2f1-6 family
M brevicollis	E2F-Mb (gi\|167523471)
	E2F1/2/3 subgroup				E2F4/5 subgroup
T. adhaerens	E2F1/2/3-Ta (gi\|196010483)				E2F4/5-Ta (gi\|196012606)
N. vectensis	E2F1/2/3-Nv (gi\|156371340)				E2F4/5-Nv (gi\|156368461)
C. elegans					EFL-1-Ce (gi\|17559226)
D.me lanogaster	E2F1-Dm (gi\|24648770)				E2F2-Dm (gi\|17137542)
S. purpuratus					E2F4/5-Sp (gi\|115696783)
C. intestinalis	E2F1/2/3-Ci (gi\|118343729)				E2F4/5-Ci (gi\|118343737)
B. floridae	E2F1/2/3-Bf (gi\|260790430)				E2F4/5-Bf (gi\|260798626)
	E2F1	E2F2	E2F3	E2F6	E2F4	E2F5
T. nigroviridis	ENSTNIT00000007876	ENSTNIT00000020634	ENSTNIT00000012687	ENSTNIT00000008935 ENSTNIT00000013829	ENSTNIT00000002389 ENSTNIT00000002758	ENSTNIT00000004791
D. rerio			gi\|220673319	gi\|71892405	gi\|47087407	gi\|68533607
X. tropicalis	ENSXETT00000046332		gi\|58331835		gi\|167560905	gi\|188528909
G. gallus	gi\|45382583		gi\|118086362	ENSGALT00000031596	gi\|118096144	gi\|71896455
R. norvegicus	gi\|189217865		gi\|212549627	gi\|109479090	ENSRNOT00000021145
M. musculus	gi\|6681243	gi\|29244208	gi\|83523736	gi\|237681138	gi\|22507329	gi\|31982405
B. taurus	gi\|194672360	gi\|76611569	gi\|76663083	gi\|116003911	gi\|115497534
C. familiaris	gi\|73992245	ENSCAFT00000021059	gi\|74004128	gi\|73980432	gi\|73957515	gi\|73999542
H. sapiens	gi\|12669911	gi\|4758226	gi\|4503433	gi\|109637795	gi\|12669915	gi\|134142811