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Table 1 Asymmetrically evolving gene pairs.

From: Asymmetric and non-uniform evolution of recently duplicated human genes

Copy evolving fast

mRNA

EST

Mutations

Copy evolving slow

mRNA

EST

Mutations

Function

[RefSeq: NM_182537]

7

0

52

[RefSeq: NM_182589]

10

0

8

Serotonin receptor

[RefSeq: NM_001083538]

3

4

29

[RefSeq: NM_001101]

230

26018

1

Actin beta

[RefSeq: NM_002030]

9

76

51

[RefSeq: NM_001005738]

12

146

15

Formyl peptide receptor

[RefSeq: NM_001009562]

16

38

77

[RefSeq: NM_019844]

12

51

34

Organic anion transporter

[RefSeq: NM_001001659]

2

0

32

[RefSeq: NM_012365]

3

0

12

Olfactory receptor

[RefSeq: NM_000896]

12

94

36

[RefSeq: NM_001082]

11

70

15

Cytochrome P450

[RefSeq: NM_152631]

3

24

64

[RefSeq: NM_001013736]

2

22

36

Unknown

[RefSeq: NM_001004692]

1

0

13

[RefSeq: NM_001004695]

3

0

2

Olfactory receptor

[RefSeq: NM_145660]

17

90

46

[RefSeq: NM_145640]

18

627

24

Apolipoprotein

[RefSeq: NM_001006938]

2

22

10

[RefSeq: NM_001006933]

6

81

1

Transcription elongation factor

[RefSeq: NM_032098]

157

856

48

[RefSeq: NM_032099]

157

856

27

Protocadherin gamma

[RefSeq: NM_001004737]

3

0

11

[RefSeq: NM_001004736]

4

0

2

Olfactory receptor

[RefSeq: NM_001004743]

1

0

37

[RefSeq: NM_001005282]

3

0

20

Olfactory receptor

[RefSeq: NM_005557]

9

464

40

[RefSeq: NM_000526]

16

1853

8

Keratin 16

[RefSeq: NM_020040]

2

1

24

[RefSeq: NM_177987]

19

2

3

Tubulin, beta polypeptide

[RefSeq: NM_002699]

4

20

15

[RefSeq: NM_006236]

1

2

0

POU class 3 homeobox

[RefSeq: NM_017534]

11

451

64

[RefSeq: NM_005963]

6

205

27

Myosin, heavy chain

[RefSeq: NM_001004482]

3

0

19

[RefSeq: NM_001004481]

3

0

2

Olfactory receptor

[RefSeq: NM_001004454]

2

0

50

[RefSeq: NM_001005236]

1

0

20

Olfactory receptor

[RefSeq: NM_001013435]

5

26

12

[RefSeq: NM_001015038]

2

16

0

P antigen family

[RefSeq: NM_000150]

15

59

26

[RefSeq: NM_002034]

4

1

6

Fucosyltransferase

[RefSeq: NM_001005479]

3

0

27

[RefSeq: NM_001005514]

1

0

7

Olfactory receptor

[RefSeq: NM_001005519]

2

0

31

[RefSeq: NM_054105]

2

0

11

Olfactory receptor

[RefSeq: NM_001005471]

1

0

34

[RefSeq: NM_030904]

1

0

15

Olfactory receptor

[RefSeq: NM_012373]

3

0

17

[RefSeq: NM_002551]

2

3

5

Olfactory receptor

[RefSeq: NM_032089]

157

856

74

[RefSeq: NM_014004]

157

856

49

Protocadherin gamma

  1. The gene pairs asymmetric by the number of non-synonymous substitutions are shown. The number of substitutions is only for non-synonymous substitutions that were acquired in this gene, when compared to its sister and cousin gene (see Methods). Data for mRNA and EST count is presented according to the UniGene database.
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