Figure 6

Graphical representation of the path analysis used to analyze the relationships among pathway positions, nonsynonymous substitution ( d _N ), d _N / d _S ratio, gene expression level, codon bias (measured by F op), protein length and protein interaction. Pathway position, protein length and connectivity were treated as exogenous variables, while the rest were treated as endogenous variables. The numbers on the arrows represent the standardized path coefficients (β). Solid and dotted lines represent significant and non-significant relationships, respectively.