Figure 11

Distribution the values of α extracted from CHIRBASE [75] (circles) and a fit (solid line) as described in the Methods with σ _ε = 0.8 (Eq. 6 and ref. 69). CHIRBASE database holds experimentally obtained retention data (about 60,000 values at 2003) which were transformed into thermodynamic association constants according to published relationships derived for quantitative affinity chromatography [87–89]. The insert shows a double logarithmic transformation of the data over a larger range, with a limiting linear slope of -1.98 and R = 0.99, in line with a lognormal distribution tail.