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Figure 4 | Biology Direct

Figure 4

From: The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

Figure 4

The origin of the small ribosomal subunit as an RNA hairpin acting in trans. A depiction of the proposed decoding hairpin, possibly ancestral to the small ribosomal subunit RNA [54], interacting with tRNAs in the ancestral A and P sites of the ancestral peptidyl transferase ribozyme [9], and a serendipitous proto-mRNA binding partner bound to the tRNA anticodon loops. Note: this view is from the opposite side of the complex to that shown in Figure 2. Adapted from the PDB files of the T. thermophilus 70S ribosome (with tRNAs and mRNA) taken from Voorhees et al. [98]. PDB files rendered using MacPyMol [99].

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