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Table 4 TK1 literature data

From: Mass action models versus the Hill model: An analysis of tetrameric human thymidine kinase 1 positive cooperativity

Ea S X V Figure Year First Author set k
8.00E-05 0.051474 2500 0.489 4 1993 MunchPetersen 1 0.20375
8.00E-05 0.097841 2500 0.861 4 1993 MunchPetersen 1 0.35875
8.00E-05 0.201282 2500 1.57 4 1993 MunchPetersen 1 0.654167
8.00E-05 0.39749 2500 2.85 4 1993 MunchPetersen 1 1.1875
8.00E-05 0.589425 2500 3.79 4 1993 MunchPetersen 1 1.579167
8.00E-05 1.005871 2500 5.14 4 1993 MunchPetersen 1 2.141667
8.00E-05 2.026393 2500 6.91 4 1993 MunchPetersen 1 2.879167
8.00E-05 3.045455 2500 8.04 4 1993 MunchPetersen 1 3.35
8.00E-05 4.033816 2500 8.35 4 1993 MunchPetersen 1 3.479167
8.00E-05 5.081395 2500 8.74 4 1993 MunchPetersen 1 3.641667
8.00E-05 5.933333 2500 8.9 4 1993 MunchPetersen 1 3.708333
8.00E-05 8.107143 2500 9.08 4 1993 MunchPetersen 1 3.783333
8.00E-05 12.37845 2500 9.42 4 1993 MunchPetersen 1 3.925
8.00E-05 19.91091 2500 8.94 4 1993 MunchPetersen 1 3.725
8.00E-05 27.90274 2500 9.18 4 1993 MunchPetersen 1 3.825
8.00E-05 64.38849 2500 8.95 4 1993 MunchPetersen 1 3.729167
2.00E-04 0.04535 2500 0.907 2a 2000 Berenstein 2 0.377917
2.00E-04 0.096983 2500 2.25 2a 2000 Berenstein 2 0.9375
2.00E-04 0.197633 2500 3.34 2a 2000 Berenstein 2 1.391667
2.00E-04 0.394156 2500 6.07 2a 2000 Berenstein 2 2.529167
2.00E-04 0.802521 2500 9.55 2a 2000 Berenstein 2 3.979167
2.00E-04 1.183486 2500 12.9 2a 2000 Berenstein 2 5.375
2.00E-04 1.587112 2500 13.3 2a 2000 Berenstein 2 5.541667
2.00E-04 2.008547 2500 14.1 2a 2000 Berenstein 2 5.875
2.00E-04 4.047619 2500 15.3 2a 2000 Berenstein 2 6.375
2.00E-04 7.819905 2500 16.5 2a 2000 Berenstein 2 6.875
2.00E-04 16.1 2500 16.9 2a 2000 Berenstein 2 7.041667
2.00E-04 24 2500 16.4 2a 2000 Berenstein 2 6.833333
2.00E-04 40 2500 16.7 2a 2000 Berenstein 2 6.958333
2.00E-04 79.9 2500 17.6 2a 2000 Berenstein 2 7.333333
2.00E-04 120 2500 16.1 2a 2000 Berenstein 2 6.708333
2.00E-04 0.0699 2500 0.342 4a 2004 Frederiksen 3 0.1425
2.00E-04 0.119 2500 1.03 4a 2004 Frederiksen 3 0.429167
2.00E-04 0.214 2500 1.92 4a 2004 Frederiksen 3 0.8
2.00E-04 0.427 2500 3.63 4a 2004 Frederiksen 3 1.5125
2.00E-04 0.846 2500 5.81 4a 2004 Frederiksen 3 2.420833
2.00E-04 1.24 2500 6.46 4a 2004 Frederiksen 3 2.691667
2.00E-04 1.65 2500 6.49 4a 2004 Frederiksen 3 2.704167
2.00E-04 2.04 2500 7.55 4a 2004 Frederiksen 3 3.145833
2.00E-04 4.05 2500 8.76 4a 2004 Frederiksen 3 3.65
2.00E-04 8.01 2500 8.62 4a 2004 Frederiksen 3 3.591667
2.00E-04 0.075862 2500 1.32 2a 2004 Li 4 0.55
2.00E-04 0.035823 2500 0.566 2a 2004 Li 4 0.235833
2.00E-04 0.198658 2500 2.96 2a 2004 Li 4 1.233333
2.00E-04 0.314729 2500 4.06 2a 2004 Li 4 1.691667
2.00E-04 0.402344 2500 5.15 2a 2004 Li 4 2.145833
2.00E-04 0.806024 2500 6.69 2a 2004 Li 4 2.7875
2.00E-04 1.007353 2500 8.22 2a 2004 Li 4 3.425
2.00E-04 1.202703 2500 8.01 2a 2004 Li 4 3.3375
2.00E-04 1.638507 2500 8.34 2a 2004 Li 4 3.475
2.00E-04 2.01467 2500 8.24 2a 2004 Li 4 3.433333
2.00E-04 9.72 2500 10.8 2a 2004 Li 4 4.5
2.00E-04 19.7 2500 11.1 2a 2004 Li 4 4.625
2.00E-04 49.7 2500 11.6 2a 2004 Li 4 4.833333
2.00E-04 100 2500 10.9 2a 2004 Li 4 4.541667
0.000306 0.0917 6000 0.012 4a 2006 Birringer 5 0.021786
0.000306 0.249 6000 0.0282 4a 2006 Birringer 5 0.051198
0.000306 0.498 6000 0.0709 4a 2006 Birringer 5 0.128722
0.000306 0.747 6000 0.0862 4a 2006 Birringer 5 0.1565
0.000306 0.996 6000 0.0883 4a 2006 Birringer 5 0.160312
0.000306 1.99 6000 0.116 4a 2006 Birringer 5 0.210603
0.000306 3 6000 0.133 4a 2006 Birringer 5 0.241467
0.000306 4.49 6000 0.127 4a 2006 Birringer 5 0.230574
0.000306 5.99 6000 0.143 4a 2006 Birringer 5 0.259622
  1. aE = TK1, S = dT and X = ATP are in total concentrations in μM. Product dTMP fluxes v are in umol/min per mg of enzyme in datasets 1-4 and in pmoles/min in the 5th dataset.