Table 1 List of E. coli SDR related enzymes and metabolic pathways.
Gene | Gene Product | Pathway | Phenotype |
|---|---|---|---|
fabG | 3-oxoacyl- [acyl-carrier-protein] reductase | fatty acid biosynthesis | synthesis of essential metabolites |
fabI | enoyl- [acyl-carrier-protein] reductase (NADH) | fatty acid biosynthesis | synthesis of essential metabolites |
hcaB | 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase | 3 phenylpropionate degradation | utilization of aromatic compounds |
srlD | glucitol (sorbitol)-6-phosphate dehydrogenase | sorbitol (glucitol) degradation | utilization of a sugar alcohol |
idnO | 5-keto-D-gluconate 5-reductase | L-idonate degradation | utilization of a sugar |
kduD* | 2-deoxy-D-gluconate 3-dehydrogenase | pentose and glucuronate interconversions | interconversion of 5- and 6-carbon carbohydrates |
hdhA | NAD-dependent 7alpha-hydroxysteroid dehydrogenase | degradation of human bile acids | decomposition of intestinal bile acids |
entA | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase | enterochelin/enterobactin biosynthesis | binds and solubilizes iron in enteric bacteria |
rfbD | dTDP-6-deoxy-L-mannose-dehydrogenase | dTDP-L-rhamnose biosynthesis | biosynthesis of enterobacterial common antigen |
rfbB | dTDP-glucose 4,6 dehydratase | dTDP-L-rhamnose biosynthesis | biosynthesis of enterobacterial common antigen |
rffG | dTDP-glucose 4,6-dehydratase 2 | dTDP-L-rhamnose biosynthesis | biosynthesis of entobacterial common antigen |
galE | UDP-galactose-4-epimerase | UDP-galactose biosynthesis | metabolism of galactose; biosynthesis of colanic acid |
fcl | GDP 4 keto 6 deoxymannose epimerase, dehydrogenase | GDP-L-fucose biosynthesis | biosynthesis of colanic acid |
gmd | GDP-D-mannose dehydratase | GDP-L-fucose biosynthesis | biosynthesis of colanic acid |
rfaD | ADP-L-glycero-D-mannoheptose-6-epimerase | ADP-L-glycero-D-mannoheptose biosynthesis | biosynthesis of Lipid A |