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Table 1 DNA and RNA stacking energies for the first 2 codond letters and the strong-weak codon classification for the 20 amino acids

From: Exceptional error minimization in putative primordial genetic codes

1st/2nd base

Amino acid

DNA melting [30, 67]

RNA stacking [68]

S/W theory [69]

GC

Ala

-2.70

-3.42

SSS

GU

Val

-2.04

-2.24

SWS

AC

Thr

-2.04

-2.24

WSS

GG

Gly

-1.97

-3.26

SSW

CC

Pro

-1.97

-3.26

SSS

GA

Asp/Glu

-1.66

-2.35

SWW

UC

Ser

-1.66

-2.35

WSS

CG

Arg

-1.44

-2.36

SSW

CU

Leu

-1.29

-2.08

SWS

AG

Ser/Arg

-1.29

-2.08

WSW

AU

Ile/Met

-1.27

-1.10

WWS

UU

Phe/Leu

-1.04

-0.93

WWS

AA

Asn/Lys

-1.04

-0.93

WWW

CA

His/Gln

-0.78

-2.11

SWW

UG

Cys/Trp

-0.78

-2.11

WSW

UA

Tyr/Stop

-0.12

-1.33

WWW