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Figure 5 | Biology Direct

Figure 5

From: Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

Figure 5

Possible mechanisms of the hypothetical novel prokaryotic systems of defense against mobile elements centered around pAgo compared to the mechanisms of CASS and eukaryotic RNAi. Currently, models (3) and/or (4) are the most likely functional mechanisms for pAgo (see text) but the eukaryotic Ago-like (1) and the prokaryotic CASS-like (2) models cannot be ruled out at this stage. RNA molecules are shown in red and DNA molecules in blue. Circles denote the proteins that form complexes with the guide RNA or DNA. Arrows indicate the directions of the respective processes.

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