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Table 2 S% Estimates under different negative selections based on YN, MYN, and γ-MYN

From: γ-MYN: a new algorithm for estimating Ka and Ks with consideration of variable substitution rates

Human Codon Frequencies
ω α Method S (%)
    κR = 1 κR = 2 κR = 3 κR = 4 κR = 5 κR = 6 κR = 7 κR = 8 κR = 9 κR = 10
0.1 4.8 YN 25.92 27.09 27.95 28.60 29.18 29.63 29.99 30.28 30.57 30.77
   MYN 29.03 28.88 28.78 28.66 28.56 28.50 28.42 28.34 28.29 28.16
   γ-MYN 29.12 28.94 28.83 28.70 28.59 28.53 28.45 28.36 28.31 28.18
0.2 4 YN 25.91 27.07 27.92 28.62 29.22 29.66 30.04 30.36 30.65 30.87
   MYN 29.00 28.87 28.69 28.57 28.53 28.43 28.30 28.26 28.21 28.15
   γ-MYN 29.10 28.95 28.75 28.62 28.57 28.47 28.33 28.28 28.23 28.16
0.3 4 YN 25.90 27.06 27.94 28.65 29.19 29.63 30.04 30.38 30.65 30.90
   MYN 29.05 28.87 28.70 28.57 28.43 28.33 28.26 28.19 28.14 28.06
   γ-MYN 29.14 28.95 28.76 28.61 28.47 28.36 28.28 28.21 28.15 28.08
0.4 3 YN 25.85 27.06 27.96 28.65 29.20 29.66 30.05 30.37 30.64 30.90
   MYN 28.96 28.84 28.70 28.55 28.44 28.35 28.27 28.22 28.16 28.10
   γ-MYN 29.08 28.94 28.78 28.62 28.50 28.40 28.31 28.25 28.18 28.11
0.5 2.5 YN 25.88 27.05 27.95 28.66 29.23 29.66 30.04 30.35 30.64 30.86
   MYN 28.97 28.81 28.68 28.56 28.47 28.36 28.29 28.18 28.15 28.05
   γ-MYN 29.12 28.93 28.77 28.63 28.53 28.41 28.33 28.21 28.17 28.07
0.6 2 YN 25.89 27.05 27.92 28.66 29.20 29.66 30.02 30.34 30.61 30.88
   MYN 28.99 28.81 28.64 28.58 28.45 28.37 28.27 28.18 28.10 28.09
   γ-MYN 29.19 28.96 28.77 28.67 28.52 28.43 28.31 28.22 28.13 28.12
0.7 1.5 YN 25.87 27.05 27.93 28.63 29.21 29.65 30.02 30.33 30.63 30.86
   MYN 28.94 28.79 28.65 28.54 28.47 28.36 28.27 28.16 28.12 28.05
   γ-MYN 29.21 28.99 28.82 28.67 28.57 28.44 28.33 28.21 28.16 28.08
0.8 1.5 YN 25.86 27.05 27.96 28.62 29.20 29.65 30.02 30.33 30.61 30.86
   MYN 28.93 28.79 28.69 28.52 28.48 28.37 28.27 28.17 28.11 28.05
   γ-MYN 29.19 29.00 28.86 28.65 28.58 28.45 28.34 28.22 28.14 28.08
0.9 1.5 YN 25.87 27.06 27.96 28.65 29.20 29.66 30.01 30.33 30.61 30.85
   MYN 28.91 28.80 28.67 28.57 28.47 28.38 28.27 28.17 28.08 28.04
   γ-MYN 29.18 29.01 28.84 28.69 28.58 28.46 28.34 28.22 28.12 28.07