Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

Table 6 Over-representation of TAS on plasmids and chromosome

TAS	Number detected on plasmids	Number detected on chromosomes	Enrichment (p < 0.01)
MazF-PHD	12	7	Plasmid
COG5654-Xre	55	195	Plasmid
MerR-PIN	9	34	Plasmid
GNAT-RHH	28	154	Plasmid
RelE-RHH	92	511	Plasmid
ArsR-COG3832	13	310	Chromosome
DUF397-Xre	3	129	Chromosome
HEPN-MNT	11	572	Chromosome
GNAT-Xre	0	67	Chromosome

The enrichment was estimated compared to the random expectation given the analyzed amount of chromosomal and plasmid sequences. The distributions of the rest of the TAS were statistically indistinguishable from the random expectation.

ISSN: 1745-6150