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Table 1 Previously characterized and new candidate TAS detected with the the first approach

From: Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

COG number

Toxin family

CV

COG number

Antitoxin family

CV

COG1848

PIN

1.1

COG8614

RHH

1.0

COG3832

Aha1 family

1.2

COG0640

ArsR family HTH

0.8

COG1708

MNT

0.9

COG2250

HEPN

1.0

COG4679

RelE

0.8

COG5606

HTH

0.6

COG2026

RelE

0.7

COG7997

MJ1172-like

0.7

COG3668

RelE

0.9

COG2161

StbD/axe

0.5

COG1708

MNT

0.4

COG2445

HEPN

0.9

COG3657

RelE

0.7

COG3636

HTH

0.6

COG1848

PIN

0.4

COG2002

AbrB/MazE/PemI

0.9

COG3668

RelE

0.9

COG3609

RHH

0.4

COG1669

MNT

0.7

COG2361

HEPN

0.6

COG9434

MazF

0.6

COG5302

CcdA

0.7

COG1598

hicB

0.7

COG1724

hicA

0.6

COG3549

RelE

0.7

COG3093

HTH

0.6

COG2026

RelE

0.4

COG2161

StbD_axe

0.9

COG3668

RelE

0.7

COG9004

RHH

0.5

COG6187

RelE

0.6

COG2944

HTH

0.6

COG1487

PIN

0.7

COG4710

RHH

0.4

COG1487

PIN

0.6

COG4456

AbrB/MazE/PemI

0.4

COG3742

PIN

0.5

COG4423

RHH

0.4

COG1487

PIN

n/a

COG5450

RHH

0.5

  1. COG numbers below 5600 correspond to the COGs that are available on the NCBI site: http://www.ncbi.nlm.nih.gov/COG/grace/uni.html
  2. COGs that were predicted to include novel toxins and antitoxins in this work are shown by bold type.
  3. CV – coefficient of variation.