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Figure 1 | Biology Direct

Figure 1

From: Pitfalls of the most commonly used models of context dependent substitution

Figure 1

Context effects are detected using TF when none exist. Sequences were simulated under a nucleotide GTR model with π (A) + π (T) ≈ 0.6. A single dinucleotide parameter for CG ⇔ NN was added to the TFnuGTR and NFnuGTR dinucleotide baseline models. The red vertical line represents the expected value under the null hypothesis (the parameter has no effect). x-axis is the MLE of CG ⇔ NN, y-axis is the number of simulated alignments.

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