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Table 2 Combined (top + next vs. not enriched +depleted) sets of miRNAs.

From: Synaptic enrichment of microRNAs in adult mouse forebrain is related to structural features of their precursors

 

Top+Next (n = 36)

Not Enriched+Depleted (n = 30)

p-value

Zone 2

   

# of stem segments

3.53 ± 0.18

2.90 ± 0.17

0.016*

Longest stem segment, nt

8.78 ± 0.54

11.3 ± 0.67

0.0043**

Bulges

3.31 ± 0.20

2.50 ± 0.17

0.0042**

Bulges ≥ 3 nt on either side

0.20 ± 0.07

0.40 ± 0.12

0.15

Symmetrical bulges

2.17 ± 0.21

1.47 ± 0.21

0.023*

Bulges 1-0 or 1-1

2.22 ± 0.22

1.40 ± 0.22

0.010**

Bulges 1-1

1.64 ± 0.20

0.80 ± 0.19

0.0045**

Zone 3

   

Bulges

1.08 ± 0.14

0.93 ± 0.17

0.50

Zones 2 and 3

   

Bulges

4.39 ± 0.27

3.43 ± 0.23

0.011*

Symmetrical bulges

2.83 ± 0.25

2.03 ± 0.23

0.023*

Bulges 1-0 or 1-1

3.0 ± 0.27

1.93 ± 0.24

0.0048**

Bulges 1-1

2.14 ± 0.22

1.13 ± 0.21

0.0015**

  1. See text for details. Values are mean ± S.E.M., and p-values were calculated using two-tailed unpaired t-test with equal variance. *significant at p = 0.05 or better. **significant at p = 0.01 or better.