Skip to main content
Figure 2 | Biology Direct

Figure 2

From: A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes

Figure 2

Hydrogen bond interactions involving insulin B chain P9 anchor in DQ8. There is a hydrogen bonding network involving the insulin peptide glutamic acid anchor and DQ8 α76 arginine, crystallographic water, β37 tyrosine, and β9 tyrosine. Two of the bonds from α76 are shown with relaxed constraints. This network of bonds hyper-stabilizes the insulin peptide.

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us