Table 7 Tight junction genes in human spermatogenesis data.
|  |  | σ μ | σ wtrep |  | ||
|---|---|---|---|---|---|---|
Gene Symbol | RefSeq ID | log2FC | P-value | log2FC | P-value | Gene Description |
ACTG1 | NM_001614 | -0.81 | 0.064 | -1.14 | 0.000 | actin, gamma 1 |
CLDN1 | NM_021101 | -2.47 | 0.059 | -1.63 | 0.000 | claudin 1 |
CLDN16 | NM_006580 | -1.20 | 0.019 | -1.55 | 0.000 | claudin 16 |
CLDN5 | NM_003277 | 1.15 | 0.286 | 1.42 | 0.000 | claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) |
CLDN6 | NM_021195 | 2.48 | 0.135 | 1.88 | 0.000 | claudin 6 |
CSNK2A2 | NM_001896 | -1.00 | 0.014 | -1.57 | 0.000 | casein kinase 2, alpha prime polypeptide |
CTNNA1 | NM_001903 | -0.93 | 0.009 | -1.04 | 0.000 | catenin (cadherin-associated protein), alpha 1, 102 kDa |
EXOC3 | NM_007277 | -1.26 | 0.019 | -1.43 | 0.000 | exocyst complex component 3 |
EXOC4 | NM_021807 | -0.78 | 0.012 | -1.04 | 0.000 | exocyst complex component 4 |
GNAI2 | NM_002070 | 1.02 | 0.110 | 1.52 | 0.000 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
JAM3 | NM_032801 | -0.86 | 0.005 | -1.07 | 0.000 | junctional adhesion molecule 3 |
KRAS | NM_004985 | -2.85 | 0.032 | -2.43 | 0.000 | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
MYH9 | NM_002473 | 1.09 | 0.183 | 1.02 | 0.000 | myosin, heavy chain 9, non-muscle |
PPP2R2B | NM_181676 | -1.22 | 0.020 | -1.97 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform |
PPP2R3A | NM_002718 | 1.42 | 0.013 | 1.50 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit B", alpha |
RAB13 | NM_002870 | -1.17 | 0.118 | -1.68 | 0.000 | RAB13, member RAS oncogene family |
TJP1 | NM_175610 | -2.63 | 0.038 | -2.10 | 0.000 | tight junction protein 1 (zona occludens 1) |
AKT3 | NM_181690 | -1.16 | 0.001 | -1.16 | 0.000 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) |
CDC42 | NM_044472 | -1.67 | 0.001 | -1.51 | 0.000 | cell division cycle 42 (GTP binding protein, 25 kDa) |
CLDN11 | NM_005602 | -2.03 | 0.000 | -2.06 | 0.000 | claudin 11 (oligodendrocyte transmembrane protein) |
CLDN14 | NM_012130 | 2.92 | 0.006 | 2.90 | 0.000 | claudin 14 |
CSDA | NM_003651 | -2.28 | 0.000 | -2.48 | 0.000 | cold shock domain protein A |
CSNK2B | NM_001320 | -2.61 | 0.006 | -2.69 | 0.000 | casein kinase 2, beta polypeptide |
CTNNA2 | NM_004389 | -1.64 | 0.002 | -1.88 | 0.000 | catenin (cadherin-associated protein), alpha 2 |
CTTN | NM_138565 | -1.91 | 0.008 | -2.05 | 0.000 | cortactin |
EPB41L3 | NM_012307 | -1.85 | 0.001 | -1.71 | 0.000 | erythrocyte membrane protein band 4.1-like 3 |
MYH10 | NM_005964 | -1.34 | 0.000 | -1.35 | 0.000 | myosin, heavy chain 10, non-muscle |
MYL6 | NM_079423 | -1.62 | 0.000 | -1.78 | 0.000 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
PPP2CA | NM_002715 | -2.69 | 0.002 | -2.40 | 0.000 | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
PPP2CB | NM_004156 | -1.43 | 0.005 | -1.83 | 0.000 | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform |
PPP2R1B | NM_181699 | -2.14 | 0.003 | -2.34 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform |
PPP2R1B | NM_181699 | -1.47 | 0.011 | -1.18 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform |
PPP2R2A | NM_002717 | -1.53 | 0.002 | -1.86 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform |
PPP2R2B | NM_181677 | 2.51 | 0.007 | 2.29 | 0.000 | protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform |
PRKCH | NM_006255 | -1.20 | 0.002 | -1.03 | 0.000 | protein kinase C, eta |
PTEN | NM_000314 | -2.30 | 0.004 | -1.61 | 0.000 | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) |
RHOA | NM_001664 | -1.81 | 0.001 | -1.58 | 0.000 | ras homolog gene family, member A |
CTNNA3 | NM_013266 | -1.03 | 0.007 | -0.92 | 0.000 | catenin (cadherin-associated protein), alpha 3 |